After a Gut Reset? Try The Best Probiotics for Women

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Bloating, constipation, and sluggish digestion: the obvious tells of an unhappy gut. But there are subtler signs that you could use a gut reset with the best probiotics for women. From brain fog to bouts of low mood, breakouts to insomnia and reduced immunity, when your gut is out of balance, your whole system follows suit.

Vogue’s Favorite Probiotics for Women

Featured in this article

Best Overall
Ritual Synbiotic+ Gut Health
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Best Synbiotic
Seed DS-01 Daily Synbiotic
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Best for Digestion
Garden of Life Once Daily Women s Probiotic
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In This Story

Enter probiotics. In short: modern society can wreak havoc on our microbiomes. Between our stressful lifestyles and the rise of ultra-processed diets, probiotic supplements have never been a more popular – or essential – defense. That said, there’s a whole lot of information out there, and in a world of lengthy bacteria names, different strains, and countless colonies, it’s easy to get confused. We’ve enlisted the experts to answer the most common gut health questions, and point us to the best probiotics for women in 2025. More on that below.

Best Overall: Ritual Synbiotic+: Probiotic, Prebiotic, Postbiotic

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Ritual

Synbiotic+ : Probiotic, Prebiotic, Postbiotic

  • Why We Love It: Ritual s Synbiotic+ is surely one of the most buzzy probiotics on the market. Its benefits come from two probiotic strains of live bacteria—Lactobacillus rhamnosus (LGG) and Bifidobacterium animalis ssp. lactis (BB-12), plus the postbiotic Tributyrin, along with the prebiotic PreforPro—housed in a delayed-release capsule, which registered dietician Mia Syn, MS, RD says makes it a comprehensive option for overall gut support. “The prebiotics feed beneficial bacteria, the probiotics help populate the gut with live strains, and the postbiotics support the gut lining and immune function,” she continues. “Together, they work synergistically to promote a balanced microbiome making it a good option for overall gut support”—from supporting healthy gut bacteria to bloating relief and improved immune health. Its three-in-one benefits make it a top pick of Sahar Berjis, registered dietitian and nutrition coach and the CEO of Inner Health Wellness: “it s efficient, stylish, and science-backed.”
Key IngredientsLactobacillus rhamnosus (LGG), Bifidobacterium animalis ssp. lactis (BB-12), PreforPro, Tributyrin
CFU Count11 billion
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO Project Verified, Clean Label Project Certified, vegan

Best for Digestion: Garden of Life Once Daily Women s Probiotic

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Garden of Life

Once Daily Women s Probiotic

Why We Love It: For Syn, this probiotic by Garden Of Life is specifically formulated to support women’s health with clinically studied strains that target digestive, immune and vaginal health—making it “a good option for women who experience recurring urinary tract infections, yeast infections or digestive irregularities who want targeted support.” Drawing up on 16 probiotic strains with 50 billion CFU, the capsule has received the approval of Berjis, recommending it for women dealing with bloating, stress, hormonal shifts, or post-antibiotic recovery. “It’s wellness in a capsule, no fancy fridge required,” she says.

Key IngredientsL. reuteri, L. fermentum, prebiotic fiber blend
CFU Count50 billion
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO Project Verified, NSF Certified, B Corp Certified

Best Synbiotic: Seed DS-01 Daily Synbiotic

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Seed

DS-01 Daily Synbiotic

Why We Love It: Seed is another ultra-popular probiotic supplement on the market right now—and for good reason. This synbiotic supplement (which means it contains both prebiotics and probiotics) is formulated to support the gut and whole body health, with the help of 24 bacteria strains. “Probiotic diversity is critical for overall health,” says Ella Davar, RD, founder of Gut-Brain Method. “Products like Seed DS-01, which offer multi-strain formulations, are excellent for increasing diversity.”

Key IngredientsBifidobacterium longum SD-BB536-JP, Bifidobacterium breve SD-BR3-IT, Lactiplantibacillus plantarum SD-LP1-IT, etc.
CFU Count53.6 billion
FormCapsule
Serving Size2 capsules
Number of Servings30
More to KnowVegan, Gluten-tested, No preservatives

Best for Women’s Health: Wisp Equalizing Probiotics

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Wisp

Equalizing Probiotics

Why We Love It: When we asked Lucky Sekhon, MD, a double-board certified reproductive endocrinologist, infertility specialist, obstetrician and gynecologist, about her favorite probiotics for women, she recommended this one by Wisp. “It contains a variety of beneficial bacteria strains that work together to promote overall wellness, enhance digestive health, and maintain a healthy balance of vaginal flora,” she says. “This supplement is particularly great for its dual-action benefits, making it a convenient option for comprehensive health support.”

Key IngredientsSaccharomyces boulardii, Lactobacillus rhamnosus, SP 1 Lactobacillus casei Lc-11, Lactobacillus paracasei Lpc-37, Lactobacillus acidophilus NCFM, Bifidobacterium lactis Bi-07, Bifidobacterium lactis Bl-04, Bifidobacterium bifidum Bb-06, Lactobacillus reuteri
CFU Count25 billion
FormTablet
Serving Size1 tablet two times per day
Number of Servings90
More to KnowN/A

Best for Metabolism: Pendulum Metabolic Daily

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Pendulum

Metabolic Daily

Why We Love It: According to registered dietitian nutritionist and founder of Compass Nutrition Adiana Castro, RD, “many of my patients have low energy and struggle with bloating, especially my female patients right before and during their menstrual cycle.” Which is where Pendulum Metabolic Daily comes in. Each capsule contains five probiotic strains to improve metabolism, strengthen the gut lining, reduce bloating, and maintain a healthy weight.

Key IngredientsClostridium butyricum, Clostridium beijerinckii, Bifidobacterium infantis, Anaerobutyricum hallii, Akkermansia muciniphila
CFU Count300 million
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO

Best for Vaginal Health: Hum Nutrition Private Party Vaginal Probiotic

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Hum Nutrition

Private Party Vaginal Probiotic

Why We Love It: If you re in search of a probiotic that prioritizes both vaginal and urinary tract health, consider Hum Nutrition s Private Party your go-to. In just one capsule per day, this delivers 10 billion CFUs through three strains of probiotics; specifically, lactobacillus acidophilus—a well-researched strain that promotes a healthy vaginal environment, plus lactobacillus rhamnosus and lactobacillus reuteri, which balance the body s pH. Cranberry extract is featured too for positive urinary benefits.

Key IngredientsLactobacillus Acidophilus, Lactobacillus Rhamnosus, Lactobacillus Reuteri, cranberry extract
CFU Count10 billion
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO Project Verified, Clean Label Project Certified, no artificial flavors, no artificial preservatives

Best for GI Health: Pendulum Akkermansia Probiotic Capsules

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Pendulum

Akkermansia Probiotic Capsules

Why We Love It: Kearny recommends this Pendulum probiotic for the featured akkermansia muciniphila—a bacteria commonly found in the human gut. “Pendulum Akkermansia contains live bacteria that helps support the intestinal lining that supports mucin production to strengthen the intestinal wall,” says Lorraine Kearney, RD, CDN, CEO of New York City Nutrition. “[This] can repair or maintain the gut lining, while also stimulating GLP-1 hormone production to support insulin and glucose levels,” says Kearny. In the brand’s clinical studies, users reported improved GI health, energy levels, and bowel movements, plus decreased sugar cravings.

Key IngredientsAkkermansia muciniphila
CFU Count100 million AFU
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO

Best for Urinary Tract Health: Metagenics UltraFlora Women s Probiotics

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Metagenics

UltraFlora Women s Probiotics

Why We Love It: “Metagenics UltraFlora Women s is a probiotic that supports the vaginal, immune, and urinary tract health,” says Kearney of this probiotic designed to support overall vaginal health. “It helps maintain a healthy vaginal pH, vaginal odor, and may decrease UTI recurrence by increasing beneficial vaginal bacteria.” This is achieved by 2 billion CFUs per serving delivered through two probiotic strains.

Key IngredientsLactobacillus rhamnosus GR-1, Lactobacillus reuteri RC-14
CFU Count2 billion
FormCapsule
Serving Size1 capsule
Number of Servings30
More to KnowNon-GMO, gluten-free, no preservatives, vegetarian

Best Greens Powder: Athletic Greens AG1

Athletic Greens

AG1

Why We Love It: Full of fiber, greens powders are gaining ground as an easier way to increase your plant intake, and Athletic Greens’ formula is one of the best supplements to invest in. While experts say it’s not a substitute for fresh wholefoods, fruit and veg, taken alongside a healthy diet it can feed your gut bacteria with generous helpings of prebiotics. The blend also contains probiotics (7.2 billion CFUs in a single scoop, to be precise) and a smorgasbord of vitamins, adaptogens, digestive enzymes and magnesium to keep you well and energised. A one-stop shop of nutrients and multivitamins, this synbiotic is best for streamlining your supplement cupboard.

Key IngredientsLactobacillus acidophilus, Bifidobacterium bifidum, Digestive Enzyme and Super Mushroom Complex, Alkaline, Nutrient-Dense Raw Superfood Complex
CFU Count10 billion
FormPowder
Serving Size1 scoop
Number of Servings30
More to KnowNSF Certified For Sport, vegan, vegetarian, gluten-free, GMO-free

Best For Constipation: Align Gut Health Immunity Support

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Align

Gut Health Immunity Support

Why We Love It: When choosing a probiotic supplement, it’s important to understand that the strain and dosage are what really impact just how effective a probiotic supplement is for a specific condition, explains Meggie Connelly RDN, LDN, owner of Be Balanced Nutrition Services. For constipation, in particular, Connelly recommends this supplement from Align. “The strain of microbe in this probiotic supplement, B. lactis BB-12, have been shown to improve constipation,” she says. What’s more, it contains Bifidobacterium lactis, a strain that naturally supports healthy immune function (since 70% of your immune system is located in your gut).

Key IngredientsBifidobacterium lactis BB-12
CFU Count5 billion
FormCapsule
Serving Size1 capsule
Number of Servings28
More to KnowVegetarian, gluten-free, no refrigeration required

Best Vegan Probiotic: Bio-K+ Advanced Bowel Support Vegan Probiotic Support

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Bio-K+

Advanced Bowel Support Vegan Probiotic Support

Why We Love It: It’s worth noting that not all supplements are inherently vegan, including probiotics. For anyone who follows a vegan diet, this Bio-K probiotic supplement is a safe bet. What’s more, it has some well-rounded gut health benefits: “The strains in this formula have been shown to help improve IBS, diarrhea associated with taking antibiotics and preventing CDiff (Clostridium difficile associated diarrhea),” says Connelly.

Key IngredientsL. acidophilus CL1285, L. casei LBC80R and L. rhamnosus CLR2
CFU Count50 billion
FormCapsule
Serving Size1 capsule
Number of Servings20
More to KnowVegan, gluten-free

Best for Heart Health: Now Supplements Heart Health Probiotic

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Now Supplements

Heart Health Probiotic

Why We Love It: That’s right, a healthy gut microbiome can support your heart, too—and certain probiotic supplements (like this particular formula from Now) may be able to help. “This is a newer product whose probiotic strain is clinically shown to maintain healthy cholesterol clearance and keep inflammation in check,” says Maggie Moon, MS, RD, a registered dietician based in Los Angeles. “For added assurance, the brand verifies the identity of each probiotic strain in their supplements using DNA-fingerprinting.”

Key IngredientsLactobacillus reuteri (LRC)
CFU Count2.5 Billion CFU
FormCapsule
Serving Size1 capsule
Number of Servings60
More to KnowVegetarian/Vegan, Non-GMO, Strain Verified

What are probiotics?

The gut is home to trillions of bacteria, which perform several functions in the human body. They aid digestion, protect against infection and synthesise neurotransmitters, such as serotonin. “Probiotics are microbes, including bacteria and yeasts, that confer a benefit to us across a variety of systems and functions,“ Rhian explains. As they naturally occur in fermented foods (think: kimchi, kefir and sauerkraut) some people question whether probiotic supplements are really necessary. But there’s good reason to invest in a quality probiotic. According to Sophie, stomach acid – which is powerful enough to corrode metal – doesn’t discriminate between good and bad bacteria. “Most of the bacteria consumed in food or liquid format is destroyed before it reaches the gut,” she says. Good probiotics ensure live bacteria survive digestion and can populate the gut.

What is the difference between probiotics and prebiotics?

Dr Megan Rossi tells us that an easy way to understand prebiotics is to think of them as “fertiliser“ for good bacteria in your gut. Fibrous foods and phytonutrients existing in fruit, veg and herbs are a great source of prebiotics. On the other hand, probiotics are the good bacteria themselves. “Generally speaking, if you’re getting a diverse range of plants in your diet – including legumes and wholegrains – then a prebiotic supplement is not typically needed,” she adds. The trouble is that modern diets often miss this mark. “On average, over half of our energy intake in the UK comes from ultra-processed foods,” says Lily Soutter, explaining that these low-fibre convenience foods are correlated with poor health markers and higher levels of bad gut bacteria. To ensure you’re getting ample prebiotics, Pow Food head nutritionist Sam Bourne recommends eating a varied diet with “30 different plant foods each week” – all of which can be found in the fresh gourmet dishes that constitute the brand’s Gut Health bundle.

What are the benefits of supplementing with probiotics?

The key thing to know is there is no one-size-fits-all effect with probiotics. But when your gut is healthy, you’ll find relief from symptoms spanning everything from indigestion to fatigue and general stomach upset. “Some of us will feel some of the more visceral benefits, like a reduction in bloating, better bowel movements, and less discomfort, within a few days,” says Rhian. “Other systemic benefits, like improvements in mood, skin, immune function, and metabolism may take longer. Some benefits of probiotics may not be noticeable at all–like their potential role in long-term illness. We now know that the health of the microbiome is implicated in a long list of disease states, including obesity, diabetes, cancer, cardiovascular disease, asthma, allergies, depression, Alzheimer’s, autoimmunity and more,” she continues. In short, supporting gut biodiversity with good bacteria from probiotics doesn’t just quell tummy troubles–it can help prevent disease and promote improved wellness overall. Below, the leading benefits of taking a probiotic.

  • Gut Health: “Probiotics help maintain the balance of good bacteria in the
    gut, which supports digestion, regular bowel movements and better
    nutrient absorption,” Syn says. “They may also help reduce bloating and symptoms of irritable bowel syndrome.”
  • Mental Health: According to Syn, “Emerging research shows that the gut and brain are closely connected: certain probiotic strains have been shown to reduce stress, anxiety and depressive symptoms by influencing the gut-brain axis.”
  • Vaginal Health: “Probiotics can help maintain a healthy vaginal microbiome
    by promoting the growth of beneficial bacteria and suppressing harmful
    organisms,” explains Syn. “Some strains have been particularly effective in reducing the risk of yeast infections and bacterial vaginosis.”

How often should women take a probiotic?

How often women should take probiotics is on individual health needs, the specific probiotic strain, and the reason for taking the supplement. “Generally, it s recommended to take a probiotic daily to maintain a consistent level of beneficial bacteria in the gut and vaginal tract,” says Sekhon. “Taking probiotics consistently at the same time each day can help enhance their effectiveness.”

How soon should you see the benefits of a probiotic?

Probiotics are not one size fits all—meaning how soon one sees benefits varies from person to person. “It usually takes around 3 months to see changes in your microbiome,” Castro explains. “However, each person is different and you may feel benefits after 1-2 months. In my experience, the best way to accelerate the microbiome changes is to feed the probiotics daily. Add prebiotics, fiber, and polyphenols to feed the probiotics daily.”

How To Choose a Probiotic

According to Kearney, “speak with a Registered Dietitian or healthcare professional before implementing probiotics to identify the correct type and quality of the probiotic. Consuming an inaccurate strain could worsen symptoms or have a negative effect on health.”

She also outlines a few other things to keep in mind during your search: “Other factors to consider include the accuracy of strength by independent third-party testing, a high number of colony-forming units (CFUs), allergen information, being free from artificial additives, storage instructions, and the shelf life of the probiotic supplement to ensure its potency and effectiveness.”

What to Look For in a Probiotic

With so many supplements on the market, finding the best one for you can be difficult. Dr Megan stresses the importance of three criteria when picking an effective probiotic: microbes have to be alive, they should be present in large numbers and crucially, have evidence of a health benefit – otherwise, they’re a waste of money and time. Look for high numbers of colony-forming units (CFU for short), which is the amount of viable bacteria in a given supplement.

Research also suggests that certain strains are more suited to different symptoms. ”Lactobacillus rhamnosus strains have been shown to benefit IBS symptoms as well as cognitive performance and mood,” says Rhian, with Dr Megan and Sophie adding that this type is especially good post antibiotics and for preventing stomach bugs. Other strains our experts recommend? Bifidobacteirum Longum for constipation, L. reuteri for UTI prevention and L. helveticus Rosell®-52, which has shown promise for alleviating stress through the reduction of cortisol. If in doubt, consult your GP for the best advice.

Kearney also cites Akkermansia muciniphila as an ingredient to look for: “Akkermansia muciniphila has been linked to lower levels of inflammation, improved glucose metabolism, and better insulin sensitivity, which are crucial in preventing metabolic disorders such as obesity and type 2 diabetes.”

What probiotic do gynecologists recommend?

“Probiotics that are good for vaginal health often contain specific types of beneficial bacteria,” Sekhon explains. “One of the most recommended strains is Lactobacillus acidophilus which can help maintain a healthy balance of bacteria in the vagina, preventing and treating bacterial vaginosis and yeast infections.” She also notes that probiotic-rich foods like yogurt with live cultures in your diet can support both vaginal and gut health.

What are the positive and negative effects of probiotics?

There are many pros to taking probioitics. “They are known to improve gut health by balancing the intestinal microbiota, which can enhance digestion and alleviate symptoms of IBS, such as bloating, gas, and diarrhea,” Sekhon says. “Additionally, probiotics can strengthen the immune system, lowering the risk of certain chronic diseases. They are also associated with improved skin conditions, like eczema.”

With all of these positives in mind, why might someone decide to steer clear of probioitics? Sekhon details that they can cause digestive issues, such as gas, bloating, and diarrhea, particularly when first introduced into the diet. “People with compromised immune systems may face a higher risk of infections due to probiotic use,” she says, noting that because the probiotic industry is not strictly regulated, the quality, and efficacy of probiotic products can vary widely, leading to inconsistent results.

Should women take a probiotic daily?

Berjis says women should absolutely take a probiotic. “Women’s microbiomes shift constantly—thanks to hormones, stress, diet, even travel,” she says. “A high-quality probiotic helps keep things balanced, from the gut to the glow.”

Per Syn, “Daily probiotic use can support consistent digestive health, help maintain a balanced vaginal microbiome and promote immune function. It may be especially beneficial for women dealing with chronic digestive issues, frequent yeast infections or recovering from antibiotic use.”

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