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Magnesium is most often associated with the sleep support and relaxation benefits provided by magnesium glycinate, a form that Moon Juice helped popularize. “Magnesium is the master mineral, and it does so much more than help with sleep,” Moon Juice founder Amanda Chantal Bacon tells Vogue. “There are dozens of different forms of magnesium, and each form determines how much you absorb and where you absorb it, what tissues it targets, and what additional effects you get from the companion molecule (this is what makes each form of magnesium unique).”
So when thinking about how to expand upon the success of the brand’s beloved Magnesi-Om powder, an integral part of the viral “sleepy-girl mocktail,” Bacon considered her own experiences. “I had long COVID in 2021, and for me that felt like nine months of crazy brain fog and recall problems,” she admits. “I struggled with mental energy, multitasking, and my creativity felt gone. It scared me—cognitive decline appears in the aging women in my family.” She goes on to explain the effects of cognitive decline—which some research suggests can start at different ages for different aspects of intelligence, with certain abilities starting to gradually decline as early as your 20s—not to mention the impacts of perimenopause. “Everyone knows that perimenopause is a reproductive transition, but fewer understand that it’s a neurological transition, too: Estrogen levels decline in the brain, which causes neurons to slow down and age faster.” So Bacon wanted to deliver a solution for whenever brain fog strikes, tapping magnesium L-threonate to power her new Neuro Magnesi-Om supplement.
“Magnesium L-threonate crosses the blood-brain barrier more effectively than other forms of magnesium,” Bacon explains. “Think of the blood-brain barrier as a screen that keeps toxins and pathogens out of your brain—it’s so selective. If not enough magnesium is getting through, you can wind up with a magnesium deficiency in your brain, which affects hormone regulation and has consequences for cognitive performance.” According to board-certified nurse practitioner Vanessa Coppola, Magtein, the brand name for magnesium L-threonate, was actually engineered for this purpose: to elevate human magnesium more effectively than conventional salts in animal models, which increased synaptic density and improved learning and memory. Unlike Moon Juice’s regular Magnesi-Om, which is ideally consumed at night before bedtime, this one’s best taken in the morning ahead of work or for an afternoon pick-me-up.
Moon Juice Neuro Magnesi-Om
- Why We Love It: Meet Moon Juice’s next magnesium supplement: Neuro Magnesi-Om. Powered by two grams of magnesium L-threonate, organic mushrooms, ceremonial-grade matcha, and L-theanine, this supplement seeks to improve cognitive function, focus, and alertness. “I want you to have regular days where the great ideas are flowing, your inbox is clearing, tasks are completing, and you have the mental stamina to read books (even with your kids) at the end of the days,” says Bacon.
- Key Ingredients: Magtein magnesium L-threonate, lion’s mane, ceremonial-grade organic matcha, L-theanine
- Size: 84 g / 2.96 oz.
To bolster its star ingredient’s benefits, the brand drew upon lion’s mane, an adaptogen central to Moon Juice’s assortment that’s known to support not just mental stamina and alertness, but overall mood as well. Then there’s ceremonial-grade matcha, L-theanine, and polyphenols. “L-theanine promotes alpha wave brain activity, reducing stress while enhancing attentional control,” Coppola says. “When paired with low-dose caffeine, it improves sustained attention, task-switching, and working memory without the jitter common to higher caffeine sources. Magnesium supports neuronal stability, sleep quality, and synaptic efficiency, while lion’s mane may encourage nerve growth factor (NGF) expression. Together, this stack targets multiple pathways: synaptic resilience (magnesium), potential neurotrophic support (lion’s mane), and attentional calm (matcha/L-theanine).” All in all, Coppola believes these ingredients work synergistically to provide balanced cognitive support for stress resilience, focus, and neuroplasticity.
Taking the supplement is quite simple. It’s a finely milled powder that blends well into hot or cold water (or milk, if you want something that’s more like a latte). One teaspoon is all you need. The flavor profile is similar to that of matcha: a little earthy, a little sweet, and more subtle than some of the brand’s other fruit-forward bestsellers. If you’re like me, you’ll be pleasantly surprised by how quickly this works. Within about 30 minutes, I felt ready to work. I breezed through emails, wrote a story quicker than usual, and felt an unexpected sharpness overall. It was the kind of brain optimization I didn’t know I needed—an effect that lasted for a few hours. If I wanted to extend this mental stamina, I could take the supplement again; Moon Juice recommends using it one to two times per day.
“We want you to feel like a genius!” Bacon says. “As always the mission is to lead with curiosity and help women get active in their health. Cognitive decline is not inevitable. The investments we start to make in our 20s, 30s, and 40s can help us stay well and present for longer.”
Meet the Experts
- Amanda Chantal Bacon is the CEO and co-founder of Moon Juice.
- Vanessa Coppola, DNP, FNP-BC is a board-certified nurse practitioner and founder of Bare Aesthetic.
