Copper Peptides Are the Anti-Aging Ingredient to Know

December 23, 2025

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Skincare devotees are always searching for the next anti-aging innovation—anything that promises to refine texture, brighten tone, or slow the visible march of time. From collagen treatments and vitamin C serums to bakuchiol and retinol, the beauty industry continues to expand its arsenal for addressing early signs of aging. The latest ingredient gaining real momentum? Copper peptides, rapidly emerging as a leading age-defying active. Below, a clear look at their origins, how they work, and why they’ve become a coveted addition to modern routines.

What are copper peptides?

Peptides, which the body naturally produces, are chains of amino acids—the fundamental building blocks of proteins. Their job is essential: like structural “bricks,” they help form proteins such as collagen and elastin, both crucial for maintaining the skin’s texture, density, and elasticity. Among the estimated billions of peptides that exist, copper peptide GHK-Cu has inspired particular excitement within cosmetic science.

“Copper peptides are a type of carrier peptide made up of copper bound to amino acids, which are the building blocks of proteins,” explains board-certified dermatologist Dr. Marisa Garshick. “Copper peptides are found naturally in the body, but their levels decline with age.”

The benefits of copper peptides

Because copper peptides occur naturally in the body, they offer a wide array of benefits when applied topically. First identified in 1973 by Dr. Loren Pickart, copper peptide GHK-Cu stands out for its remarkable anti-aging capacity. It is known to stimulate collagen synthesis, helping maintain the skin’s firmness and resilience while slowing visible aging. A 1998 study from the Reims Faculty of Medicine found that collagen production increased by 70% after one month of applying this peptide—compared with a 40% increase from tretinoin. Subsequent studies have further illustrated its benefits.

“In skincare, copper peptides help signal the skin to support collagen and elastin production, which can improve firmness, texture, and the appearance of fine lines and wrinkles,” says Garshick. “They also have antioxidant properties, help support wound healing, and promote the production of glycosaminoglycans such as hyaluronic acid, which enhances hydration.”

How to use copper peptides

Incorporating products with copper peptides into your skincare routine is simple: begin with applications every other day to allow the skin to adjust, then increase frequency as your skin’s tolerance and visible results guide you.

As far as which formulations are best, Garshick recommends looking for products that pair copper peptides with barrier-supporting and hydrating ingredients, “as this helps maximize both tolerability and results.” She particularly likes the Mother Science Molecular Genesis Barrier Repair Moisturizer, which combines copper peptides with the brand’s patented ingredient Malassezin, along with hyaluronic acid, lipids, squalane, and growth factors (“It is an excellent option for patients looking to improve signs of aging while also prioritizing barrier repair and overall skin health,” she says) and DRMTLGY’s Needle-less Serum, which contains copper peptides, ceramides, niacinamide, and hyaluronic acid.